AIMC Topic: Cytochrome P-450 CYP2C9 Inhibitors
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Evaluation of machine learning models for cytochrome P450 3A4, 2D6, and 2C9 inhibition.
Journal of applied toxicology : JAT
Mar 27, 2024
Cytochrome P450 (CYP) enzymes are involved in the metabolism of approximately 75% of marketed drugs. Inhibition of the major drug-metabolizing P450s could alter drug metabolism and lead to undesirable drug-drug interactions. Therefore, it is of great...
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