AIMC Topic: E1A-Associated p300 Protein

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Enhancing the Predictive Power of Machine Learning Models through a Chemical Space Complementary DEL Screening Strategy.

Journal of medicinal chemistry Oct 23, 2024
DNA-encoded library (DEL) technology is an effective method for small molecule drug discovery, enabling high-throughput screening against target proteins. While DEL screening produces extensive data, it can reveal complex patterns not easily recogniz...
Humans Machine Learning Drug Discovery Transcription Factors DNA High-Throughput Screening Assays Cell Cycle Proteins Small Molecule Libraries E1A-Associated p300 Protein Bromodomain Containing Proteins
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eRFSVM: a hybrid classifier to predict enhancers-integrating random forests with support vector machines.

Hereditas Jun 30, 2016
BACKGROUND: Enhancers are tissue specific distal regulation elements, playing vital roles in gene regulation and expression. The prediction and identification of enhancers are important but challenging issues for bioinformatics studies. Existing comp...
Humans Algorithms Support Vector Machine Cell Line Histones Enhancer Elements, Genetic E1A-Associated p300 Protein
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