AIMC Topic: Genes, Synthetic

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AI-directed gene fusing prolongs the evolutionary half-life of synthetic gene circuits.

Science advances
Evolutionary instability is a persistent challenge in synthetic biology, often leading to the loss of heterologous gene expression over time. Here, we present STABLES, a gene fusion strategy that links a gene of interest (GOI) to an essential endogen...

Protein design meets biosecurity.

Science (New York, N.Y.)
The power and accuracy of computational protein design have been increasing rapidly with the incorporation of artificial intelligence (AI) approaches. This promises to transform biotechnology, enabling advances across sustainability and medicine. DNA...