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Hemolytic Agents

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A Web Server and Mobile App for Computing Hemolytic Potency of Peptides.

Scientific reports
Numerous therapeutic peptides do not enter the clinical trials just because of their high hemolytic activity. Recently, we developed a database, Hemolytik, for maintaining experimentally validated hemolytic and non-hemolytic peptides. The present stu...

HemoPred: a web server for predicting the hemolytic activity of peptides.

Future medicinal chemistry
AIM: Toxicity arising from hemolytic activity of peptides hinders its further progress as drug candidates.

HAPPENN is a novel tool for hemolytic activity prediction for therapeutic peptides which employs neural networks.

Scientific reports
The growing prevalence of resistance to antibiotics motivates the search for new antibacterial agents. Antimicrobial peptides are a diverse class of well-studied membrane-active peptides which function as part of the innate host defence system, and f...