AIMC Topic: Hemolytic Agents

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HAPPENN is a novel tool for hemolytic activity prediction for therapeutic peptides which employs neural networks.

Scientific reports Jul 2, 2020
The growing prevalence of resistance to antibiotics motivates the search for new antibacterial agents. Antimicrobial peptides are a diverse class of well-studied membrane-active peptides which function as part of the innate host defence system, and f...
Humans Neural Networks, Computer Machine Learning Software Computer Simulation Antimicrobial Cationic Peptides Hemolysis Sequence Analysis, Protein Hemolytic Agents
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HemoPred: a web server for predicting the hemolytic activity of peptides.

Future medicinal chemistry Feb 17, 2017
AIM: Toxicity arising from hemolytic activity of peptides hinders its further progress as drug candidates.
Humans Machine Learning Software Computer Simulation Peptides Databases, Protein Amino Acid Sequence Hemolysis Hemolytic Agents
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A Web Server and Mobile App for Computing Hemolytic Potency of Peptides.

Scientific reports Mar 8, 2016
Numerous therapeutic peptides do not enter the clinical trials just because of their high hemolytic activity. Recently, we developed a database, Hemolytik, for maintaining experimentally validated hemolytic and non-hemolytic peptides. The present stu...
Humans Computer Simulation Peptides Mobile Applications Support Vector Machine Databases, Protein Internet Amino Acid Sequence Hemolysis Sequence Analysis, Protein Hemolytic Agents
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