AIMC Topic: Hot Melt Extrusion Technology

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Application of rheology to hot melt extrusion: Theory and practice.

International journal of pharmaceutics May 29, 2025
Hot melt extrusion (HME) has become a key manufacturing method in the pharmaceutical industry for developing novel drug delivery systems, due to its solvent-free nature, ease of operation, and ability to achieve one-step molding and continuous proces...
Drug Delivery Systems Printing, Three-Dimensional Polymers Rheology Drug Compounding Technology, Pharmaceutical Viscosity Chemistry, Pharmaceutical Excipients Hot Melt Extrusion Technology
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Delineating the effects of hot-melt extrusion on the performance of a polymeric film using artificial neural networks and an evolutionary algorithm.

International journal of pharmaceutics Sep 24, 2019
The aim of this study was to utilize an artificial neural network (ANN) in conjunction with an evolutionary algorithm to investigate the relationship between hot melt extrusion (HME) process parameters and vaginal film performance. Investigated HME p...
Neural Networks, Computer Drug Carriers Polymers Drug Liberation Drug Compounding Chemistry, Pharmaceutical Hot Temperature Hot Melt Extrusion Technology
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