Recent advances in artificial intelligence (AI) and machine learning (ML) are revolutionizing nanopharmaceutical development by enabling data-driven formulation design, process optimization, and prediction of biological performance. AI encompasses co...
Recently, pharmaceutical cocrystal technology has garnered considerable global attention because of its innovativeness and environmental sustainability. This technology effectively enhances the bioavailability of poorly soluble drugs and optimizes th...
International journal of pharmaceutics
Dec 16, 2025
The mutual benefits of surface engineering and crystal engineering led to the discovery of a pharmaceutical cocrystal with balanced biopharmaceutical properties. The surface engineering of a pharmaceutical API (Active Pharmaceutical Ingredient), name...
Efficient determination of developable protein drug candidates and stable solution conditions is a key challenge in industrial drug development. Protein aggregation is difficult to predict and can lead to challenges in manufacturing, storage, and pat...
Since Pfizer developed the mRNA vaccine for COVID-19 by leveraging artificial intelligence (AI) for designing the vaccine, integrating AI and allied domains in the drug development process has escalated at an unimaginable rate. Owing to the complex a...
International journal of pharmaceutics
Nov 25, 2025
Defining suspension stability can be extremely complex, but beyond critical during the formulation development of nano- and microsuspensions intended for long-acting injectables. As of now, the current practice is based on the trial-and-error approac...
International journal of pharmaceutics
Nov 24, 2025
Over the past two decades, a diverse array of ultrasonic and acoustic elastic-wave techniques has been developed to non-destructively assess macro- and micro-scale properties of compressed Oral Solid Dosage (OSD) forms. These methods are increasingly...
International journal of pharmaceutics
Nov 4, 2025
Liposomes have transformed drug delivery by enhancing the solubility, stability, and bioavailability of therapeutic agents, driving widespread clinical adoption and contributing to a rapidly expanding multi-billion-dollar market. However, despite the...
The liquid and solid formulations of self-nano-emulsifying drug delivery systems (SNEDDS) have garnered significant attention in the pharmaceutical field for their ability to enhance the solubility and absorption of hydrophobic drugs. While both liqu...
Integrating machine learning (ML) into nanotechnology represents a promising strategy for rational design and accelerated development of drug delivery systems. However, studies in this field are scarce and face methodological and interpretative probl...
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