AIMC Topic: Molecular Sequence Annotation

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A Machine Learning Approach for Accurate Annotation of Noncoding RNAs.

IEEE/ACM transactions on computational biology and bioinformatics
Searching genomes to locate noncoding RNA genes with known secondary structure is an important problem in bioinformatics. In general, the secondary structure of a searched noncoding RNA is defined with a structure model constructed from the structura...

P-Finder: Reconstruction of Signaling Networks from Protein-Protein Interactions and GO Annotations.

IEEE/ACM transactions on computational biology and bioinformatics
Because most complex genetic diseases are caused by defects of cell signaling, illuminating a signaling cascade is essential for understanding their mechanisms. We present three novel computational algorithms to reconstruct signaling networks between...