AIMC Topic: NAV1.7 Voltage-Gated Sodium Channel

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An artificial intelligence accelerated virtual screening platform for drug discovery.

Nature communications Sep 5, 2024
Structure-based virtual screening is a key tool in early drug discovery, with growing interest in the screening of multi-billion chemical compound libraries. However, the success of virtual screening crucially depends on the accuracy of the binding p...
Humans Artificial Intelligence Molecular Docking Simulation Drug Discovery Protein Binding Drug Evaluation, Preclinical Ligands Crystallography, X-Ray Ubiquitin-Protein Ligases Small Molecule Libraries NAV1.7 Voltage-Gated Sodium Channel
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ML-based Models as a Strategy to Discover Novel Antiepileptic Drugs Targeting Sodium Receptor Channel.

Current topics in medicinal chemistry Jan 1, 2025
BACKGROUND: Epilepsy remains the most common and chronic disorder demanding longterm management. The impact of epilepsy disease is a cause of great concern and has resulted in efforts to develop treatment for epilepsy. It occurs due to an increase in...
Humans Machine Learning Drug Discovery Epilepsy Anticonvulsants NAV1.7 Voltage-Gated Sodium Channel
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