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Preparation of arginine-glycine-aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization.

International journal of nanomedicine 28115846
Neovascularization (NV) of the cornea can disrupt visual function, causing ocular diseases, including blindness. Therefore, treatment of corneal NV has a high public health impact. Epigalloccatechin-3-gallate (EGCG), presenting antiangiogenesis effec...
Angiogenesis Inhibitors Animals Burns, Chemical Catechin Cell Survival Corneal Neovascularization Disease Models, Animal Eye Burns Human Umbilical Vein Endothelial Cells Humans Hyaluronic Acid Integrin alphaVbeta3 Mice, Inbred C57BL Molecular Targeted Therapy Nanoparticles Oligopeptides Ophthalmic Solutions
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