AIMC Topic: Prophages

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Similar Prophage Induction but Divergent Antibiotic Resistance Gene Occurrence: Leachates and Free Radicals Drive Differential Activation Mechanisms in Aged Tire Crumb Rubber.

Environmental science & technology
Indigenous phages play a key role in the spread of extracellular antibiotic resistance genes (eARGs), and micro/nanocontaminants can exacerbate this process. However, the specific roles and mechanisms of phage communities in this process are still no...

Machine learning predicts new anti-CRISPR proteins.

Nucleic acids research
The increasing use of CRISPR-Cas9 in medicine, agriculture, and synthetic biology has accelerated the drive to discover new CRISPR-Cas inhibitors as potential mechanisms of control for gene editing applications. Many anti-CRISPRs have been found that...

Machine-Learning Classification Suggests That Many Alphaproteobacterial Prophages May Instead Be Gene Transfer Agents.

Genome biology and evolution
Many of the sequenced bacterial and archaeal genomes encode regions of viral provenance. Yet, not all of these regions encode bona fide viruses. Gene transfer agents (GTAs) are thought to be former viruses that are now maintained in genomes of some b...