AIMC Topic: Receptors, Purinergic P2X7

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Deep learning structural insights into heterotrimeric alternatively spliced P2X7 receptors.

Purinergic signalling
P2X7 receptors (P2X7Rs) are membrane-bound ATP-gated ion channels that are composed of three subunits. Different subunit structures may be expressed due to alternative splicing of the P2RX7 gene, altering the receptor's function when combined with th...