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Smad7 Protein

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Model based on GA and DNN for prediction of mRNA-Smad7 expression regulated by miRNAs in breast cancer.

Theoretical biology & medical modelling
BACKGROUND: The Smad7 protein is negative regulator of the TGF-β signaling pathway, which is upregulated in patients with breast cancer. miRNAs regulate proteins expressions by arresting or degrading the mRNAs. The purpose of this work is to identify...