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Thyroxine-Binding Globulin

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Machine learning to improve false-positive results in the Dutch newborn screening for congenital hypothyroidism.

Clinical biochemistry
OBJECTIVE: The Dutch Congenital hypothyroidism (CH) Newborn Screening (NBS) algorithm for thyroidal and central congenital hypothyroidism (CH-T and CH-C, respectively) is primarily based on determination of thyroxine (T4) concentrations in dried bloo...