AIMC Topic: Trypanosoma

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Superior Auto-Identification of Trypanosome Parasites by Using a Hybrid Deep-Learning Model.

Journal of visualized experiments : JoVE Oct 27, 2023
Trypanosomiasis is a significant public health problem in several regions across the world, including South Asia and Southeast Asia. The identification of hotspot areas under active surveillance is a fundamental procedure for controlling disease tran...
Neural Networks, Computer Artificial Intelligence Animals Deep Learning Parasites Trypanosoma
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Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery.

Biochemical Society transactions Feb 27, 2023
Trypanosomatids are protozoan parasites that cause human and animal neglected diseases. Despite global efforts, effective treatments are still much needed. Phenotypic screens have provided several chemical leads for drug discovery, but the mechanism ...
Humans Artificial Intelligence Animals Drug Design Drug Discovery Genomics Genome Trypanosoma
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Positive Predictive Value Surfaces as a Complementary Tool to Assess the Performance of Virtual Screening Methods.

Mini reviews in medicinal chemistry Jan 1, 2020
BACKGROUND: Since their introduction in the virtual screening field, Receiver Operating Characteristic (ROC) curve-derived metrics have been widely used for benchmarking of computational methods and algorithms intended for virtual screening applicati...
Machine Learning Animals ROC Curve Area Under Curve Seizures Anticonvulsants Protozoan Proteins Quantitative Structure-Activity Relationship 4-Aminobutyrate Transaminase Trypanosoma
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