Neurological insights into brain-targeted cancer therapy and bioinspired microrobots.

Journal: Drug discovery today
Published Date:

Abstract

Cancer, a multifaceted and pernicious disease, continuously challenges medicine, requiring innovative treatments. Brain cancers pose unique and daunting challenges due to the intricacies of the central nervous system and the blood-brain barrier. In this era of precision medicine, the convergence of neurology, oncology, and cutting-edge technology has given birth to a promising avenue - targeted cancer therapy. Furthermore, bioinspired microrobots have emerged as an ingenious approach to drug delivery, enabling precision and control in cancer treatment. This Keynote review explores the intricate web of neurological insights into brain-targeted cancer therapy and the paradigm-shifting world of bioinspired microrobots. It serves as a critical and comprehensive overview of these evolving fields, aiming to underscore their integration and potential for revolutionary cancer treatments.

Authors

  • Shampa Ghosh
    GloNeuro, Sector 107, Vishwakarma Road, Noida, Uttar Pradesh 201301, India.
  • Rakesh Bhaskar
    School of Chemical Engineering, Yeungnam University, Gyeonsang 38541, Republic of Korea; Research Institute of Cell Culture, Yeungnam University, Gyeonsang 38541, Republic of Korea.
  • Richa Mishra
    Department of Computer Science and Engineering, Parul University, Vadodara, Gujrat 391760, India.
  • M Arockia Babu
    Institute of Pharmaceutical Research, GLA University, Mathura, India.
  • Mosleh Mohammad Abomughaid
    Department of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Bisha, Bisha 61922, Saudi Arabia.
  • Niraj Kumar Jha
    Centre of Research Impact and Outcome, Chitkara University, Rajpura 140401, Punjab, India; Centre for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India; School of Bioengineering & Biosciences, Lovely Professional University, Phagwara 144411, India; Department of Biotechnology Engineering and Food Technology, Chandigarh University, Mohali, India. Electronic address: nirajkumarjha2011@gmail.com.
  • Jitendra Kumar Sinha
    GloNeuro, Sector 107, Vishwakarma Road, Noida, Uttar Pradesh 201301, India. Electronic address: jksinha@gloneuro.org.