Serum and Wound Vancomycin Levels After Intrawound Administration in Primary Total Joint Arthroplasty.

Journal: The Journal of arthroplasty
PMID: 27633945

Abstract

BACKGROUND: Periprosthetic joint infection is the most common cause of readmissions after total joint arthroplasty (TJA). Intrawound vancomycin powder (VP) has reduced infection rates in spine surgery; however, there are no data regarding VP in primary TJA.

Authors

  • Jeremiah D Johnson
    Department of Orthopaedic Surgery, Regions Hospital, St. Paul, Minnesota; Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota.
  • Joseph M Nessler
    Creighton University School of Medicine, Omaha, Nebraska.
  • Ryan D Horazdovsky
    Department of Orthopaedic Surgery, Regions Hospital, St. Paul, Minnesota; Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota.
  • Sandy Vang
    Department of Orthopaedic Surgery, Regions Hospital, St. Paul, Minnesota; Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota.
  • Avis J Thomas
    HealthPartners Institute for Education and Research, Bloomington, Minnesota.
  • Scott B Marston
    Department of Orthopaedic Surgery, Regions Hospital, St. Paul, Minnesota; Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, Minnesota.

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