Improving the Quality of Unstructured Cancer Data Using Large Language Models: A German Oncological Case Study.

Journal: Studies in health technology and informatics
PMID:

Abstract

With cancer being a leading cause of death globally, epidemiological and clinical cancer registration is paramount for enhancing oncological care and facilitating scientific research. However, the heterogeneous landscape of medical data presents significant challenges to the current manual process of tumor documentation. This paper explores the potential of Large Language Models (LLMs) for transforming unstructured medical reports into the structured format mandated by the German Basic Oncology Dataset. Our findings indicate that integrating LLMs into existing hospital data management systems or cancer registries can significantly enhance the quality and completeness of cancer data collection - a vital component for diagnosing and treating cancer and improving the effectiveness and benefits of therapies. This work contributes to the broader discussion on the potential of artificial intelligence or LLMs to revolutionize medical data processing and reporting in general and cancer care in particular.

Authors

  • Yongli Mou
    RWTH Aachen University, Germany.
  • Jonathan Lehmkuhl
    Chair of Computer Science 5, RWTH Aachen University, Germany.
  • Nicolas Sauerbrunn
    Center for Integrated Oncology, University Hospital Aachen, Germany.
  • Anja Köchel
    Center for Integrated Oncology, University Hospital Aachen, Germany.
  • Jens Panse
    Center for Integrated Oncology, University Hospital Aachen, Germany.
  • Daniel Truh
    Department of Diagnostic and Interventional Radiology, University Hospital Aachen, Germany.
  • Sulayman Sowe
    Chair of Computer Science 5, RWTH Aachen University, Germany.
  • Tim Brümmendorf
    Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, University Hospital Aachen, Germany.
  • Stefan Decker
    Institute for Biomedical Informatics, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.