Abnormal postcentral gyrus voxel-mirrored homotopic connectivity as a biomarker of mild cognitive impairment: A resting-state fMRI and support vector machine analysis.

Journal: Experimental gerontology
PMID:

Abstract

BACKGROUND: While patients affected by mild cognitive impairment (MCI) exhibit characteristic voxel-mirrored homotopic connectivity (VMHC) alterations, the ability of such VMHC abnormalities to predict the diagnosis of MCI in these patients remains uncertain. As such, this study was performed to evaluate the potential role of VMHC abnormalities in the diagnosis of MCI.

Authors

  • Ziruo Li
    Department of General Practice, Tianyou Hospital, Affiliated to Wuhan University of Science and Technology, Wuhan 430064, Hubei, China.
  • Chunyan Huang
    Department of General Practice, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
  • Xingfu Zhao
    Wuxi Mental Health Center, Nanjing Medical University, Wuxi 214151, Jiangsu, China.
  • Yujun Gao
    Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan, China.
  • Shenglan Tian
    Department of General Practice, Tianyou Hospital, Affiliated to Wuhan University of Science and Technology, Wuhan 430064, Hubei, China. Electronic address: wkdtsl@wust.edu.cn.