Use of machine learning algorithms to determine the relationship between air pollution and cognitive impairment in Taiwan.

Journal: Ecotoxicology and environmental safety
PMID:

Abstract

Air pollution has become a major global threat to human health. Urbanization and industrialization over the past few decades have increased the air pollution. Plausible connections have been made between air pollutants and dementia. This study used machine learning algorithms (k-nearest neighbors, random forest, gradient-boosted decision trees, eXtreme gradient boosting, and CatBoost) to investigate the association between cognitive impairment and air pollution. Data from the Taiwan Biobank and 75 air-pollution-monitoring stations in Taiwan were analyzed to determine individual levels of exposure to air pollutants. The pollutants examined were particulate matter with a diameter of ≤ 2.5 μm (PM), nitrogen dioxide, nitric oxide, carbon monoxide, and ozone. The results revealed that the most strongly correlated with cognitive impairment were ozone, PM, and carbon monoxide levels with adjustment of educational level, age, and household income. The model based on these factors achieved accuracy as high as 0.97 for detecting cognitive impairment, indicating a positive association between air pollutions and cognitive impairment.

Authors

  • Cheng-Hong Yang
    Department of Electronic Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, Taiwan. chyang@cc.kuas.edu.tw.
  • Chih-Hsien Wu
    Department of Electronic Engineering, National Kaohsiung University of Science and Technology, Kaohsiung 80778, Taiwan.
  • Kuei-Hau Luo
    Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan.
  • Huang-Chih Chang
    Divisions of Pulmonary & Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 83341, Taiwan; Ph.D Program in Environmental and Occupational Medicine, and Research Center for Environmental Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan. Electronic address: kuan2101@yahoo.com.tw.
  • Sz-Chiao Wu
    Epidemiology in the Public Health Program, College of Health, Oregon State University, Oregon 97331, USA. Electronic address: wusz550@gmail.com.
  • Hung-Yi Chuang
    Department of Occupational and Environmental Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung City, Taiwan.