AIMC Topic: Nitric Oxide
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Detection of Breath Nitric Oxide at Ppb Level Based on Multiperiodic Spectral Reconstruction Neural Network.
Analytical chemistry
Jan 29, 2025
As breath nitric oxide (NO) is a biomarker of respiratory inflammation, reliable techniques for the online detection of ppb-level NO in exhaled breath are essential for the noninvasive diagnosis of respiratory inflammation. Here, we report a breath N...
Estrogen-mediated modulation of sterile inflammatory markers and baroreflex sensitivity in ovariectomized female Wistar rats.
Archives of endocrinology and metabolism
Nov 6, 2024
OBJECTIVE: This study aims to explore the role of estrogen in providing cardioprotective benefits to premenopausal women, examining how hormonal differences between sexes influence the prevalence of cardiovascular diseases (CVDs) in women.
Selective Identification of Hazardous Gases Using Flexible, Room-Temperature Operable Sensor Array Based on Reduced Graphene Oxide and Metal Oxide Nanoparticles via Machine Learning.
ACS sensors
Oct 29, 2024
Selective detection and monitoring of hazardous gases with similar properties are highly desirable to ensure human safety. The development of flexible and room-temperature (RT) operable chemiresistive gas sensors provides an excellent opportunity to ...
Use of machine learning algorithms to determine the relationship between air pollution and cognitive impairment in Taiwan.
Ecotoxicology and environmental safety
Aug 15, 2024
Air pollution has become a major global threat to human health. Urbanization and industrialization over the past few decades have increased the air pollution. Plausible connections have been made between air pollutants and dementia. This study used m...
High-Content Image-Based Screening and Deep Learning for the Detection of Anti-Inflammatory Drug Leads.
Chembiochem : a European journal of chemical biology
Nov 7, 2023
We developed a high-content image-based screen that utilizes the pro-inflammatory stimulus lipopolysaccharide (LPS) and murine macrophages (RAW264.7) with the goal of enabling the identification of novel anti-inflammatory lead compounds. We screened ...
Nitric oxide releasing polyvinyl alcohol and sodium alginate hydrogels as antibacterial and conductive strain sensors.
International journal of biological macromolecules
Apr 23, 2023
Conductive hydrogels have promising applications in flexible electronic devices and artificial intelligence, which have attracted much attention in recent years. However, most conductive hydrogels have no antimicrobial activity, inevitably leading to...
Mul-SNO: A Novel Prediction Tool for S-Nitrosylation Sites Based on Deep Learning Methods.
IEEE journal of biomedical and health informatics
May 5, 2022
Protein s-nitrosylation (SNO) is one of the most important post-translational modifications and is formed by the covalent modification of nitric oxide and cysteine residues. Extensive studies have shown that SNO plays a pivotal role in the plant immu...
Anti-Inflammatory Activity of Sanjie Zhentong Capsule Assessed By Network Pharmacology Analysis of Adenomyosis Treatment.
Drug design, development and therapy
Feb 20, 2020
BACKGROUND: Sanjie Zhentong capsule (SZC) offers excellent effect in treating adenomyosis (AM), which is a common and difficult gynecological disease in the clinic. However, the systematic analysis of its mechanism has not been carried out yet and fu...
Antioxidant and Anti-inflammatory Diagnostic Biomarkers in Multiple Sclerosis: A Machine Learning Study.
Molecular neurobiology
Jan 22, 2020
An imbalance of inflammatory/anti-inflammatory and oxidant/antioxidant molecules has been implicated in the demyelination and axonal damage in multiple sclerosis (MS). The current study aimed to evaluate the plasma levels of tumor necrosis factor (TN...
Advanced Oxidation Protein Products
Nitrosative Stress
Humans
Receptors, Tumor Necrosis Factor
Neural Networks, Computer
Antioxidants
Nitric Oxide
Inflammation
Support Vector Machine
Oxidation-Reduction
Sulfhydryl Compounds
Multiple Sclerosis
Adiponectin
Tumor Necrosis Factor-alpha
Sensitivity and Specificity
Biomarkers
Male
Female
Middle Aged
Adult
Oxidative Stress
The Effect of the Prethanol Extract of Trifolium pratense Leaves on Interleukin-1β-Induced Cartilage Matrix Degradation in Primary Rat Chondrocytes.
Cells, tissues, organs
Jan 31, 2019
BACKGROUND: Osteoarthritis (OA) is a degenerative joint disease, characterized by cartilage degradation and inflammation. The proinflammatory cytokine, interleukin (IL)-1β, plays a crucial role in the pathogenesis of OA by inducing the release of oth...
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