Artificial intelligence-driven volumetric CT outcome score in cystic fibrosis: longitudinal and multicenter validation with/without modulators treatment.

Journal: European radiology
PMID: 39150489

Abstract

OBJECTIVES: Holistic segmentation of CT structural alterations with 3D deep learning has recently been described in cystic fibrosis (CF), allowing the measurement of normalized volumes of airway abnormalities (NOVAA-CT) as an automated quantitative outcome. Clinical validations are needed, including longitudinal and multicenter evaluations.

Authors

  • Amel Imene Hadj Bouzid
    CERIST, Research Center on Scientific and Technical Information, Algiers, Algeria.
  • Stephanie Bui
    Bordeaux University Hospital, Hôpital Pellegrin-Enfants, Paediatric Cystic Fibrosis Reference Center (CRCM), CIC 1401, Bordeaux, France.
  • Ilyes Benlala
    Faculté de Médecine, Université de Bordeaux, 33000 Bordeaux, France.
  • Patrick Berger
    Université de Bordeaux, INSERM, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, Bordeaux, France.
  • Antoine Hutt
    Department of Thoracic Imagining-Hospital Calmette, University Center of Lille.
  • Renan Liberge
    Department of Radiology, CHU Nantes, 44000 Nantes, France.
  • Paul Habert
    Imaging Department, Hopital La Timone, APHM, Aix Marseille University, Marseille, France.
  • Jean-Yves Gaubert
    Imaging Department, Hopital La Timone, APHM, Aix Marseille University, Marseille, France.
  • Marie Baque-Juston
    Paediatric Radiology Department, Hôpitaux Pédiatriques de Nice CHU-Lenval, Nice, France.
  • Baptiste Morel
    Pediatric Radiology Department, Clocheville Hospital, CHRU de Tours, Tours, France.
  • Gilbert Ferretti
    Universite Grenobles Alpes, Service de Radiologie et Imagerie Médicale, CHU Grenoble-Alpes, 38000 Grenoble, France.
  • Baudouin Denis de Senneville
    Université de Bordeaux, Mathematical Institute of Bordeaux (IMB), UMR CNRS 5251, Talence, France.
  • François Laurent
    Service d'imagerie thoracique, hôpital du Haut Lévêque, F-33600 Pessac, France.
  • Julie Macey
    CHU Bordeaux, Service d'Imagerie Thoracique et Cardiovasculaire, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, CIC 1401, Pessac, France.
  • Gael Dournes
    Faculté de Médecine, Université de Bordeaux, 33000 Bordeaux, France.

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