Exploration of the shared diagnostic genes and mechanisms between periodontitis and primary Sjögren's syndrome by integrated comprehensive bioinformatics analysis and machine learning.

Journal: International immunopharmacology

PMID: 39142001

Abstract

BACKGROUND: Accumulating evidence has showed a bidirectional link between periodontitis (PD) and primary Sjögren's syndrome (pSS), but the mechanisms of their occurrence remain unclear. Hence, this study aimed to investigate the shared diagnostic genes and potential mechanisms between PD and pSS using bioinformatics methods.

Authors

Shaoru Wang

Institute of Stomatology, Binzhou Medical University, Yantai 264003, China; Hospital of Stomatology, Jilin University, Changchun 130000, China.
Qimin Wang

Department of Stomatology, Qingdao Municipal Hospital, Qingdao 266071, China.
Kai Zhao

Department of Gastroenterology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shengchao Zhang

Lab of Tissue Engineering, College of Life Sciences, Northwest University, Xi'an 710069, China. Electronic address: zhangshengchao0601@163.com.
Zhenggang Chen

Institute of Stomatology, Binzhou Medical University, Yantai 264003, China; The affiliated Yantai Stomatological Hospital, Binzhou Medical University, Yantai 264003, China. Electronic address: chenzhg1973@163.com.

Keywords

Computational Biology Databases, Genetic Gene Expression Profiling Gene Regulatory Networks Humans Machine Learning MicroRNAs Periodontitis Receptors, CXCR4 Sjogren's Syndrome

External Resources

View on PubMed Access via DOI PubMed (39142001)

Exploration of the shared diagnostic genes and mechanisms between periodontitis and primary Sjögren's syndrome by integrated comprehensive bioinformatics analysis and machine learning.

Abstract

Authors

Keywords

External Resources

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