AIMC Topic: Periodontitis
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Bioinformatics analysis of Rho-signal transduction genes in postmenopausal osteoporosis and periodontitis.
Scientific reports
Aug 5, 2025
Postmenopausal osteoporosis (PMOP) increases the risk of periodontitis (PD), yet the shared mechanisms remain unclear. Rho-signal transduction genes may play a role due to their involvement in bone remodeling. This study aimed to explore Rho-related ...
Integrated network toxicology, machine learning and molecular docking reveal the mechanism of benzopyrene-induced periodontitis.
BMC pharmacology & toxicology
Jun 6, 2025
BACKGROUND: Environmental pollutants, particularly from air pollution and tobacco smoke, have emerged as significant risk factors. Benzopyrene (BaP), a Group 1 carcinogen, is ubiquitously present in these pollutants, yet its molecular mechanisms in p...
Integrated bioinformatics, machine learning, and molecular docking reveal crosstalk genes and potential drugs between periodontitis and systemic lupus erythematosus.
Scientific reports
May 6, 2025
Evidence indicates a connection between periodontitis (PD) and systemic lupus erythematosus (SLE), though the underlying co-morbid mechanisms remain unclear. This study sought to identify the genetic factors and potential therapeutic agents involved ...
Identification and Validation of Ferritinophagy-Related Biomarkers in Periodontitis.
International dental journal
Apr 15, 2025
OBJECTIVE: While ferritinophagy is believed to play a significant role in the development of periodontitis, the exact mechanisms remain unclear. This study aimed to investigate the biomarkers associated with ferritinophagy in periodontitis using tran...
Deciphering the Pharmacological Potential of Kouqiangjie Formula for the Treatment of Diabetic Periodontitis Based on Network Pharmacology, Machine Learning, Molecular Dynamics, and Animal Experiments.
Drug design, development and therapy
Mar 20, 2025
BACKGROUND: Periodontitis (PD) and type 2 diabetes mellitus (T2DM) represent interlinked global health burdens, commonly causing significant clinical complications when coincident. Therefore, managing both conditions (T2DM with periodontitis, DP) sim...
Emerging Applications of Digital Technologies for Periodontal Screening, Diagnosis and Prognosis in the Dental Setting.
Journal of clinical periodontology
Mar 19, 2025
AIM: To comprehensively review digital technologies (including artificial intelligence, AI) for periodontal screening, diagnosis and prognosis in the dental setting, focusing on accuracy metrics.
Artificial intelligence models for periodontitis classification: A systematic review.
Journal of dentistry
Mar 17, 2025
OBJECTIVES: The graded diagnosis of periodontitis has always been a difficulty for dentists. This systematic review aimed to investigate the performance of artificial intelligence (AI) models for periodontitis classification.
Estimating Periodontal Stability Using Computer Vision.
Journal of dental research
Mar 16, 2025
Periodontitis is a severe infection affecting oral and systemic health and is traditionally diagnosed through clinical probing-a process that is time-consuming, uncomfortable for patients, and subject to variability based on the operator's skill. We ...
Identification of Gingival Inflammation Surface Image Features Using Intraoral Scanning and Deep Learning.
International dental journal
Jan 27, 2025
INTRODUCTION AND AIM: The assessment of gingival inflammation surface features mainly depends on subjective judgment and lacks quantifiable and reproducible indicators. Therefore, it is a need to acquire objective identification information for accur...
Analysis of the basement membrane-related genes ITGA7 and its regulatory role in periodontitis via machine learning: a retrospective study.
BMC oral health
Dec 24, 2024
BACKGROUND: Periodontitis is among the most prevalent inflammatory conditions and greatly impacts oral health. This study aimed to elucidate the role of basement membrane-related genes in the pathogenesis and diagnosis of periodontitis.
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