This study aimed to investigate the molecular mechanisms of periodontitis and identify key immune-related biomarkers using machine learning and Mendelian randomization (MR). Differentially expressed gene (DEG) analysis was performed on periodontitis ...
BACKGROUND: is widely recognised as a periodontal pathogen. In recent years, there has been growing interest in the use of medicinal plant extracts as alternative treatments for periodontitis to combat the emergence of antibiotic-resistant bacteria....
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
40346842
Vimentin, an abundant intracellular cytoskeletal protein, is secreted into the extracellular space, where it can amplify tissue destruction in inflammatory diseases. The mechanisms by which inflammation promotes the release of extracellular vimentin ...
BACKGROUND: Periodontitis is among the most prevalent inflammatory conditions and greatly impacts oral health. This study aimed to elucidate the role of basement membrane-related genes in the pathogenesis and diagnosis of periodontitis.
AIM: To analyse the risk factors contributing to the prevalence of periodontitis among clusters of patients with diabetes and to examine the clustering patterns of clinical blood biochemical indicators.
BACKGROUND: Periodontitis (PD) and type 2 diabetes mellitus (T2DM) represent interlinked global health burdens, commonly causing significant clinical complications when coincident. Therefore, managing both conditions (T2DM with periodontitis, DP) sim...
INTRODUCTION AND AIM: The assessment of gingival inflammation surface features mainly depends on subjective judgment and lacks quantifiable and reproducible indicators. Therefore, it is a need to acquire objective identification information for accur...
OBJECTIVES: Periodontitis is a serious periodontal infection that damages the soft tissues and bone around teeth and is linked to systemic conditions. Accurate diagnosis and staging, complemented by radiographic evaluation, are vital. This systematic...
OBJECTIVES: The graded diagnosis of periodontitis has always been a difficulty for dentists. This systematic review aimed to investigate the performance of artificial intelligence (AI) models for periodontitis classification.
Evidence indicates a connection between periodontitis (PD) and systemic lupus erythematosus (SLE), though the underlying co-morbid mechanisms remain unclear. This study sought to identify the genetic factors and potential therapeutic agents involved ...