Mapping vaccine names in clinical trials to vaccine ontology using cascaded fine-tuned domain-specific language models.

Journal: Journal of biomedical semantics
PMID: 39123237

Abstract

BACKGROUND: Vaccines have revolutionized public health by providing protection against infectious diseases. They stimulate the immune system and generate memory cells to defend against targeted diseases. Clinical trials evaluate vaccine performance, including dosage, administration routes, and potential side effects.

Authors

  • Jianfu Li
    Mayo Clinic.
  • Yiming Li
    Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, China.
  • Yuanyi Pan
    Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  • Jinjing Guo
    Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
  • Zenan Sun
    McWilliams School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Fang Li
    Department of General Surgery, Chongqing General Hospital, Chongqing, China.
  • Yongqun He
    University of Michigan Medical School, Ann Arbor, MI 48109 USA ; Unit for Laboratory Animal Medicine, Department of Microbiology and Immunology, Center for Computational Medicine and Bioinformatics, and Comprehensive Cancer Center, University of Michigan Medical School, 1301 MSRB III, 1150 W. Medical Dr., Ann Arbor, MI 48109 USA.
  • Cui Tao
    The University of Texas Health Science Center at Houston, USA.

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