AIMC Topic: Vaccines
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Advances in vaccine adjuvant development and future perspectives.
Drug delivery
Jun 19, 2025
Use of highly purified antigens to improve vaccine safety has led to reduced immunogenicity and efficacy, resulting in the need for adjuvants to increase and/or modulate the immunogenicity of the vaccine. Despite the need for potent and safe vaccine ...
Bayesian optimization and machine learning for vaccine formulation development.
PloS one
Jun 11, 2025
Developing vaccines with a better stability is an area of improvement to meet the global health needs of preventing infectious diseases. With the advancement of data science and artificial intelligence, innovative approaches have emerged. This manusc...
Vaccinology in the artificial intelligence era.
Science translational medicine
Apr 16, 2025
Artificial intelligence (AI) has already transformed vaccine antigen design and could transform the entire vaccinology pipeline, including immune responses and emerging infectious disease prediction, manufacturing and regulatory processes, clinical t...
Mapping vaccine names in clinical trials to vaccine ontology using cascaded fine-tuned domain-specific language models.
Journal of biomedical semantics
Aug 10, 2024
BACKGROUND: Vaccines have revolutionized public health by providing protection against infectious diseases. They stimulate the immune system and generate memory cells to defend against targeted diseases. Clinical trials evaluate vaccine performance, ...
Leveraging artificial intelligence in vaccine development: A narrative review.
Journal of microbiological methods
Jul 15, 2024
Vaccine development stands as a cornerstone of public health efforts, pivotal in curbing infectious diseases and reducing global morbidity and mortality. However, traditional vaccine development methods are often time-consuming, costly, and inefficie...
Vaccine design and development: Exploring the interface with computational biology and AI.
International reviews of immunology
Jul 10, 2024
Computational biology involves applying computer science and informatics techniques in biology to understand complex biological data. It allows us to collect, connect, and analyze biological data at a large scale and build predictive models. In the t...
Use of artificial intelligence in vaccine development against pathogens: Challenges and future directions.
Indian journal of pharmacology
Apr 30, 2024
Ontological representation, modeling, and analysis of parasite vaccines.
Journal of biomedical semantics
Apr 25, 2024
BACKGROUND: Pathogenic parasites are responsible for multiple diseases, such as malaria and Chagas disease, in humans and livestock. Traditionally, pathogenic parasites have been largely an evasive topic for vaccine design, with most successful vacci...
Reverse engineering protection: A comprehensive survey of reverse vaccinology-based vaccines targeting viral pathogens.
Vaccine
Mar 23, 2024
Vaccines have significantly reduced the impact of numerous deadly viral infections. However, there is an increasing need to expedite vaccine development in light of the recurrent pandemics and epidemics. Also, identifying vaccines against certain vir...
Construction of an aerolysin-based multi-epitope vaccine against an machine learning and artificial intelligence-supported approach.
Frontiers in immunology
Mar 1, 2024
, a gram-negative coccobacillus bacterium, can cause various infections in humans, including septic arthritis, diarrhea (traveler's diarrhea), gastroenteritis, skin and wound infections, meningitis, fulminating septicemia, enterocolitis, peritonitis,...
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