Establishment of diagnostic model and identification of diagnostic markers between liver cancer and cirrhosis based on multi-chip and machine learning.

Journal: Clinical and experimental pharmacology & physiology
PMID: 38965675

Abstract

OBJECTIVE: Most cases of hepatocellular carcinoma (HCC) arise as a consequence of cirrhosis. In this study, our objective is to construct a comprehensive diagnostic model that investigates the diagnostic markers distinguishing between cirrhosis and HCC.

Authors

  • Tianpeng Yang
    School of Public Health, Wenzhou Medical University, Wenzhou, China.
  • Lu Huang
    School of Food Science and Technology, Dalian Polytechnic University, National Engineering Research Center of Seafood, Dalian 116034, PR China.
  • Jiale He
    School of Public Health, Wenzhou Medical University, Wenzhou, China.
  • Lihong Luo
    School of Public Health, Wenzhou Medical University, Wenzhou, China.
  • Weiting Guo
    School of Public Health, Wenzhou Medical University, Wenzhou, China.
  • Huajian Chen
    School of Public Health, Wenzhou Medical University, Wenzhou, China.
  • Xinyue Jiang
    School of Public Health, Wenzhou Medical University, Wenzhou, China.
  • Li Huang
    National Research Center for Resettlement (NRCR), Hohai University, 1 Xikang Road, Nanjing 210098, China. lily8214@hhu.edu.cn.
  • Shumei Ma
    School of Public Health, Wenzhou Medical University, Wenzhou, China.
  • Xiaodong Liu
    Academy of Fine Arts, Linyi University, Linyi, Shandong 276000, China.

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