Development, study, and comparison of models of cross-immunity to the influenza virus using statistical methods and machine learning.

Journal: Voprosy virusologii
PMID:

Abstract

INTRODUCTION: The World Health Organization considers the values of antibody titers in the hemagglutination inhibition assay as one of the most important criteria for assessing successful vaccination. Mathematical modeling of cross-immunity allows for identification on a real-time basis of new antigenic variants, which is of paramount importance for human health.

Authors

  • M N Asatryan
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • I S Shmyr
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • B I Timofeev
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • D N Shcherbinin
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • V G Agasaryan
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • T A Timofeeva
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • I F Ershov
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • E R Gerasimuk
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • A V Nozdracheva
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • T A Semenenko
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • D Y Logunov
    National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamaleya.
  • A L Gintsburg
    National Research Centre for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya, Ministry of Health of the Russian Federation, Moscow, 123098 Russian Federation.