Artificial intelligence-based analysis of behavior and brain images in cocaine-self-administered marmosets.

Journal: Journal of neuroscience methods
PMID: 39306012

Abstract

BACKGROUND: The sophisticated behavioral and cognitive repertoires of non-human primates (NHPs) make them suitable subjects for studies involving cocaine self-administration (SA) schedules. However, ethical considerations, adherence to the 3Rs principle (replacement, reduction and refinement), and other factors make it challenging to obtain NHPs individuals for research. Consequently, there is a need for methods that can comprehensively analyze small datasets using artificial intelligence (AI).

Authors

  • Wonmi Gu
    College of Pharmacy, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do 28160, Republic of Korea.
  • Juhui Gim
    College of Pharmacy, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do 28160, Republic of Korea.
  • Dohyun Lee
    Non-clinical Center, Osong Medical Innovation Foundation, 123 Osongsaengmyeong-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do 28160, Republic of Korea.
  • Heejong Eom
    Non-clinical Center, Osong Medical Innovation Foundation, 123 Osongsaengmyeong-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do 28160, Republic of Korea.
  • Jae Jun Lee
    Institute of New Frontier Research, Hallym University College of Medicine, Chuncheon, Korea.
  • Seong Shoon Yoon
    College of Korean Medicine, Daegu Haany University, 136 Sincheondong-ro, Suseong-gu, Daegu 42158, Republic of Korea.
  • Tae-Young Heo
    Department of Information & Statistics, Chungbuk National University, Chungdae-Ro 1, SeoWon-Gu, Cheongju, Chungbuk 28644, Republic of Korea. Electronic address: theo@cbnu.ac.kr.
  • Jaesuk Yun
    College of Pharmacy, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do 28160, Republic of Korea. Electronic address: jyun@chungbuk.ac.kr.

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