Identification of Staphylococcus aureus, Enterococcus faecium, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii from Raman spectra by Artificial Intelligent Raman Detection and Identification System (AIRDIS) with machine learning.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
PMID: 39638747

Abstract

BACKGROUND: Rapid and accurate identification of bacteria is required in order to develop effective treatment strategies. Traditional culture-based methods are time-consuming, while MALDI-TOF MS is expensive. The Raman spectroscopy, due to its relatively cost-effectiveness, offers a promising alternative for bacterial identification. However, its clinical utility still requires further validation.

Authors

  • Yu-Tzu Lin
    Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan.
  • Hsiu-Hsien Lin
    Department of Laboratory Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan.
  • Chih-Hao Chen
    Stroke Center and Department of Neurology National Taiwan University Hospital Taipei Taiwan.
  • Kun-Hao Tseng
    Department of Laboratory Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan.
  • Pang-Chien Hsu
    Department of Laboratory Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan.
  • Ya-Lun Wu
    Artificial Intelligence Center, China Medical University Hospital, No. 2, Yude Rd, North Dist, Taichung, Taiwan.
  • Wei-Cheng Chang
    ITRUST MedTech Inc., Hsinchu, Taiwan.
  • Nai-Shun Liao
    ITRUST MedTech Inc., Hsinchu, Taiwan.
  • Yi-Fan Chou
    ITRUST MedTech Inc., Hsinchu, Taiwan.
  • Chun-Yi Hsu
    ITRUST MedTech Inc., Hsinchu, Taiwan.
  • Yu-Hui Liao
    ITRUST MedTech Inc., Hsinchu, Taiwan.
  • Mao-Wang Ho
    Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan.
  • Shih-Sheng Chang
    AI Innovation Center, China Medical University Hospital, Taichung City, Taiwan.
  • Po-Ren Hsueh
    Department of Laboratory Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan; Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan. Electronic address: hsporen@gmail.com.
  • Der-Yang Cho
    Department of Neurosurgery, China Medical University Hospital, Taichung, Taiwan.

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