UNLABELLED: Matrix-assisted laser desorption-ionization-time of flight (MALDI-TOF) mass spectra can be used to predict antimicrobial resistance (AMR) using machine learning (ML). This study aimed to validate the performance of ML models for AMR predi...
Antimicrobial resistance and infection control
Nov 18, 2025
BACKGROUND: The transmission of antibiotic-resistant bacteria in intensive care units (ICUs) poses a significant challenge to infection control and patient safety. While direct patient-to-patient transmission is well documented, the relative contribu...
Bacterial antimicrobial resistance (AMR) poses a significant public health threat. The increase of both global awareness and affordable whole genome sequencing has yielded an ever-growing collection of bacterial genome sequence datasets and correspon...
Marine biotechnology (New York, N.Y.)
Oct 30, 2025
Antimicrobial resistance is a serious threat to global public health and requires new therapeutic approaches. Antimicrobial peptides (AMP) are recognized as promising candidates to address antimicrobial resistance. AMP can disrupt cell membranes by i...
UNLABELLED: is one of the most frequently reported healthcare-associated pathogens. The current gold standard approach to perform the epidemiological typing of these bacteria is Whole Genome Sequencing (WGS), which is an expensive and challenging pr...
Molecular genetics and genomics : MGG
Sep 29, 2025
Antimicrobial resistance (AMR) presents a critical global challenge, causing over 1.27 million deaths annually, with projections reaching 10 million by 2050. Among the most concerning contributors are Enterobacteriaceae, particularly Escherichia coli...
Healthcare-associated infections (HAIs), particularly in neonatal intensive care units (NICUs), pose significant challenges due to neonates' vulnerability and the rapid infection spread. However, risk factors facilitating pathogen persistence and dis...
Metabolomics : Official journal of the Metabolomic Society
Aug 12, 2025
INTRODUCTION: The degree of antimicrobial resistance demonstrated by carbapenemase-producing Enterobacterales (CPE) represents a growing public health challenge. Conventional methods for detecting CPE involve culture-based techniques with lengthy inc...
The emergence of Carbapenem-resistant (CRKP) represents a major public health concern, primarily driven by its ability to evade a wide range of antibiotics. Despite extensive genomic studies, proteomic insights into antibiotic resistance mechanisms ...
Rapid antimicrobial susceptibility testing (RAST) using disk diffusion (DD) from positive blood cultures (BC) can aid initiation of effective antimicrobial therapy. Rapid molecular blood culture identification panels (BCID) and microbiology laborator...
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