AIMC Topic: Staphylococcus aureus

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Cell death-related gene signatures as dual-function biomarkers: Early diagnosis and therapeutic targeting in Staphylococcus aureus pneumonia.

PloS one
BACKGROUND: Staphylococcus aureus (S. aureus) pneumonia constitutes a lethal respiratory infection with persistently high clinical mortality. Although programmed cell death (PCD) pathways are implicated in diverse disease processes, their mechanistic...

Large-scale characterisation of the nasal microbiome redefines Staphylococcus aureus colonisation status.

Nature communications
Staphylococcus aureus colonises the nose in humans, with individuals defined as persistent, intermittent or non-carriers. Unlike the gut microbiome, the nasal microbiome has not been studied in large numbers of people. Here, we define the nasal micro...

Prediction of antimicrobial resistance from MALDI-TOF mass spectra using machine learning: a validation study.

Journal of clinical microbiology
UNLABELLED: Matrix-assisted laser desorption-ionization-time of flight (MALDI-TOF) mass spectra can be used to predict antimicrobial resistance (AMR) using machine learning (ML). This study aimed to validate the performance of ML models for AMR predi...

Flexible Porous ACH/Ag Surface-Enhanced Raman Scattering Platform for Sensitive Detection and Machine-Learning-Assisted Classification of Multiple Pathogenic Bacteria.

Analytical chemistry
Pathogenic bacteria pose serious threats to public health and environmental safety. Conventional colony counting, a standard method for bacterial detection, is time-consuming and unsuitable for rapid on-site detection. In this work, a flexible ACH/Ag...

Portable AI-driven electrochemical aptasensor for real-time Staphylococcus aureus detection in food and beverages.

Mikrochimica acta
A portable electrochemical aptasensor integrated with machine learning was developed for rapid and on-site detection of Staphylococcus aureus (S. aureus) in food and beverage samples. The aptasensor was fabricated using screen-printed carbon electrod...

Analysis of disruptive action of electrical current on cell membrane integrity and modelling its antimicrobial activity.

Archives of microbiology
It is essential to eliminate harmful microbes from vital aspects of our lives, including dental instruments and other healthcare devices, cosmetics, foods, and products that come into contact with them. Electrical stimulation (ES) has been proposed t...

Machine Learning-Assisted Terahertz Metagrating Biosensor for Label-Free Bacterial Identification Based on Spectral Fingerprinting.

Analytical chemistry
Rapid and accurate identification of pathogenic bacteria is pivotal for enabling early clinical diagnosis and precision antimicrobial therapy. In this study, we developed a label-free bacterial detection platform that integrates terahertz (THz) metag...

AI verification for spirulina's antimicrobial power in total coliform and Staphylococcus aureus isolated from tilapia fillet.

Scientific reports
Seafood products, including fresh tilapia fillets, are highly susceptible to rapid quality deterioration due to microbial contamination, posing a significant concern for food safety and public health. This study investigated, both experimentally and ...

Overcoming Immune Evasion in : Strategies for Rational Vaccine Design.

ACS infectious diseases
remains one of the most elusive targets in bacterial vaccinology, primarily due to its complex immune evasion strategies and the phenomenon of immune imprinting. Despite decades of research and numerous clinical trials, no vaccine has demonstrated p...

Bioinspired Multifunctional Eutectogels for Skin-Like Flexible Strain Sensors with Potential Application in Deep-Learning Handwriting Recognition.

Langmuir : the ACS journal of surfaces and colloids
Polymerizable deep eutectic solvents (PDES) have recently emerged as a class of solvent-free ionically conductive elastomers and are considered among the most feasible candidates for next-generation ionotronic devices. However, the fundamental challe...