An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor.

Journal: Magnesium research
Published Date:

Abstract

PURPOSE: Magnesium is an important electrolyte for very many cell functions and its deficiency may lead to a wide spectrum of diseases. We report a clinical case of hypomagnesemia resulting from the chronic use of a proton pump inhibitor (PPI). PPIs are drugs widely used in medical practice, and a growing number of cases of PPIs causing hypomagnesemia have been described. Our aim was to monitor the clinical and electrolyte findings during recovery from hypomagnesemia caused by long-term PPI use.

Authors

  • Lívia Marcela dos Santos
    Laboratory of Molecular and Translational Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil, Bone Metabolism Unit, Endocrinology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
  • Ricardo Ayello Guerra
    Endocrinology Unit, Hospital do Servidor Público do Estado de São Paulo (HSPE-IAMSPE), São Paulo, Brazil.
  • Marise Lazaretti-Castro
    Bone Metabolism Unit, Endocrinology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
  • José Gilberto H Vieira
    Laboratory of Molecular and Translational Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil, Bone Metabolism Unit, Endocrinology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
  • Evandro de Souza Portes
    Endocrinología, Hospital do Servidor Público Estadual (IAMSPE), São Paulo, SP Brasil.
  • Magnus R Dias-da-Silva
    Laboratory of Molecular and Translational Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.