Machine learning based on alcohol drinking-gut microbiota-liver axis in predicting the occurrence of early-stage hepatocellular carcinoma.

Journal: BMC cancer
PMID:

Abstract

BACKGROUND: Alcohol drinking and gut microbiota are related to hepatocellular carcinoma (HCC), but the specific relationship between them remains unclear.

Authors

  • Yi Yang
    Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Zhiyuan Bo
    Department of Surgery, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Jingxian Wang
    Human Phenome Institute, Fudan University, Shanghai, China.
  • Bo Chen
  • Qing Su
    Department of Epidemiology and Biostatistics, School of Public Health, Fudan University, Shanghai, China.
  • Yiran Lian
    The Second Clinical School of Wenzhou Medical University, Wenzhou, China.
  • Yimo Guo
    Clinical Medicine, Renji College, Wenzhou Medical University, Wenzhou, China.
  • Jinhuan Yang
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
  • Chongming Zheng
    Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
  • Juejin Wang
    Department of Epidemiology and Biostatistics, School of Public Health, Wenzhou Medical University, Wenzhou, 325035, China.
  • Hao Zeng
    European Laboratory for Non Linear Spectroscopy (LENS), University of Florence, 50019 Sesto Fiorentino, Italy.
  • Junxi Zhou
    Department of Epidemiology and Biostatistics, School of Public Health, Wenzhou Medical University, Wenzhou, 325035, China.
  • Yaqing Chen
    Affiliated Xiaoshan Hospital, Hangzhou Normal University, Hangzhou, China.
  • Gang Chen
    Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Yi Wang
    Department of Neurology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.