ASSOCIATION BETWEEN MURINE DOUBLE MINUTE 2 - T309G polymorphism and recurrence of hepatocellular carcinoma after surgical treatment.

Journal: Arquivos de gastroenterologia
PMID: 26840476

Abstract

BACKGROUND: Discovery and incorporation of biomarker panels to cancer studies enabled the understanding of genetic variation and its interference in carcinogenesis at molecular level. The potential association between single nucleotide polymorphism (SNP) 309 and increased development of tumors, such as hepatocellular carcinoma, has been subject to several studies. This is the first study on this association conducted in Brazil.

Authors

  • Uirá Fernandes Teixeira
    Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brasil.
  • Andréa Gomes Coelho Izaguirre
    Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brasil.
  • Mayara Christ Machry
    Universidade Federal de Ciências da Saúde de Porto Alegre, RS, Brasil.
  • Carlos Thadeu Cerski
    Departamento de Patologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
  • Ajácio Bandeira de Mello Brandão
    Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brasil.
  • Paulo Roberto Ott Fontes
    Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brasil.

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