Predicting local control of brain metastases after stereotactic radiotherapy with clinical, radiomics and deep learning features.

Journal: Radiation oncology (London, England)
PMID:

Abstract

BACKGROUND AND PURPOSE: Timely identification of local failure after stereotactic radiotherapy for brain metastases allows for treatment modifications, potentially improving outcomes. While previous studies showed that adding radiomics or Deep Learning (DL) features to clinical features increased Local Control (LC) prediction accuracy, their combined potential to predict LC remains unexplored. We examined whether a model using a combination of radiomics, DL and clinical features achieves better accuracy than models using only a subset of these features.

Authors

  • Hemalatha Kanakarajan
    Department of Cognitive Neuropsychology, Tilburg University, Tilburg, The Netherlands. H.Kanakarajan@tilburguniversity.edu.
  • Wouter De Baene
    Department of Cognitive Neuropsychology, Tilburg University, Tilburg, The Netherlands.
  • Patrick Hanssens
    Gamma Knife Center, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
  • Margriet Sitskoorn
    Department of Cognitive Neuropsychology, Tilburg University, Tilburg, The Netherlands. M.M.Sitskoorn@tilburguniversity.edu.