A machine learning model for predicting abnormal liver function induced by a Chinese herbal medicine preparation (Zhengqing Fengtongning) in patients with rheumatoid arthritis based on real-world study.

Journal: Journal of integrative medicine
PMID: 39721810

Abstract

OBJECTIVE: Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects the small joints of the whole body and degrades the patients' quality of life. Zhengqing Fengtongning (ZF) is a traditional Chinese medicine preparation used to treat RA. ZF may cause liver injury. In this study, we aimed to develop a prediction model for abnormal liver function caused by ZF.

Authors

  • Ze Yu
    Beijing Medicinovo Technology Co. Ltd., Beijing, China.
  • Fang Kou
    Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
  • Ya Gao
    BGI-Shenzhen, Shenzhen, China.
  • Fei Gao
    College of Biological Sciences, China Agricultural University, Beijing 100193, China.
  • Chun-Ming Lyu
    Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: chunming83g@126.com.
  • Hai Wei
    School of Computer Science and Technology, Dalian University of Technology, Dalian 116024, China. weihai_dlut@163.com.

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