Hepatocellular carcinoma (HCC) poses a significant global health burden with limited therapeutic efficacy. Chinese herbal medicines (CHMs) offer multi-target potential, yet their systematic screening and mechanistic elucidation remain challenging. We...
- Herbal Pair (SEHP) is one of the classic Chinese herbal formulas for treating Alzheimer's disease (AD), but its complex chemical composition renders traditional analytical methods inefficient. Retention time (RT) provides complementary information ...
The global consumption of Citri reticulatae pericarpium (Chenpi, CP) and Citrus reticulata 'chachi' (Guangchenpi, GCP) has been experiencing a steady increase, driven by its extensive applications in healthcare, flavoring, and therapeutic fields. Whi...
BACKGROUND: Intervertebral disc degeneration (IDD) is prevalent in orthopaedics, yet lacks effective treatments. This study seeks to discover potential therapeutic targets for IDD to inform clinical therapies and traditional medicine approaches.
Lupus nephritis (LN), a severe renal complication of systemic lupus erythematosus (SLE), results from immune abnormalities. Qingre Kasen granules (QS), which have chicory as the main ingredient, play a significant role in treating various inflammator...
BACKGROUND: Dietary management and nephrotoxic herbal medicine control are essential and sophisticated in chronic kidney disease(CKD) care. Information gap between clinical principles and real-world practice hinders the relevant management. It is nec...
Phytomedicine : international journal of phytotherapy and phytopharmacology
Oct 30, 2025
BACKGROUND: Target identification is fundamental to drug discovery, facilitating mechanistic elucidation and therapeutic target identification. Traditional herbal medicines exert therapeutic effects through multi-component, multi-target synergistic m...
Given the growing demand for Gastrodiae Rhizoma (GR), it is important to establish a strategy for origin authentication and adulteration screening to ensure the high-quality products in the market. Currently, efficient and dependable methods for iden...
Journal of pharmaceutical and biomedical analysis
Oct 22, 2025
Sinapis Semen, as a traditional Chinese medicine, has an unclear relationship between its stir-frying degrees and sensory characteristics. Therefore, it is essential to develop a multi-index evaluation method to classify the processing degree of Sina...
Phytomedicine : international journal of phytotherapy and phytopharmacology
Oct 15, 2025
BACKGROUND: Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease with rising prevalence and limited therapies. Zhilining Formula (ZLN), a Traditional Chinese Medicine (TCM), shows clinical efficacy in UC, yet its core material b...
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