[A Case of Advanced Gastric Cancer with Peritoneal Dissemination Effectively Treated with S-1 and Docetaxel Combination Chemotherapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy
PMID:

Abstract

A 72-year-old man underwent surgery for advanced gastric cancer. Systemic chemotherapy was started, using a regimen of S-1/CDDP for 4 courses, followed by 8 courses of S-1. Three years and 8 months after the surgery, abdominal CT demonstrated ascites, and the serum CA19-9 level was abnormally high (1,165.1 U/mL). Adenocarcinoma cells were found in the ascites. Treatment with S-1/docetaxel (DOC) was started. After 10 courses, the ascites disappeared and the serum CA19-9 value returned to normal. Four years and 7 months after the operation, the patient has been in good health, with no signs of recurrence.

Authors

  • Hiroyuki Saito
    Laboratory of Biophysical Chemistry, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan.
  • Yuki Suematsu
  • Miyuki Hiratsuka
  • Hiroshi Suda
  • Miyuki Takahashi
  • Keita Omori
  • Yuji Ishibashi
    Department of Gastroenterology and Minimally Invasive Surgery, Juntendo University Hospital, Juntendo University School of Medicine, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan. yj-ishibashi@juntendo.ac.jp.
  • Akihiko Morita
  • Kazuhiko Wakabayashi
  • Yutaka Ito