PURPOSE: To evaluate differences in clinical outcomes, treatments received, recurrence, and sociodemographic characteristics in patients with triple-negative breast cancer (TNBC) classified as invasive lobular carcinoma (TNBC-ILC) or invasive carcino...
European journal of cancer (Oxford, England : 1990)
Sep 12, 2025
PURPOSE: To establish machine learning-based predictive models for rapidly progressive nasopharyngeal carcinoma (RP-NPC), defined as disease progression within 24 months post-initial treatment, and to assess differential survival benefits of adjuvant...
BACKGROUND: Most models of neoadjuvant chemotherapy (NACT) for breast cancer (BC) suffer from insufficient data and lack interpretability. Additionally, there is a notable absence of reports from China in this field. This study is also the first to i...
BACKGROUND AND AIMS: Breast cancer remains the most common cancer among women globally, with neoadjuvant chemotherapy (NAC) serving as a critical pre-surgical intervention. Ultrasound-based radiomics and machine learning (ML) models offer potential f...
Although neoadjuvant chemotherapy with docetaxel + cisplatin + 5-fluorouracil (CF) has been the standard treatment for stage II and III esophageal cancers, it is associated with severe adverse events caused by docetaxel. Consequently, this study aime...
BACKGROUND: Neoadjuvant chemotherapy (NAC) can improve the prognosis of patients with locally advanced gastric cancer (LAGC). However, precise models for accurate prognostic predictions are lacking. We aimed to utilize Cox regression and integrate va...
BACKGROUND: Neoadjuvant chemotherapy (NAC) is gaining attention as a treatment for advanced colorectal cancer owing to its potential to improve surgical outcomes and prognosis. However, reliable biomarkers to predict the response to NAC are lacking. ...
BACKGROUND: Time/resource constraints might preclude a randomized controlled trial. Single-arm oncology trials with historical controls are an alternative. With causal inference, treatment effect estimates can be computed in the absence of randomizat...
AIM: To develop and validate a combined model based on magnetic resonance imaging (MRI), and whole-slide imaging (WSI) to predict pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in breast cancer.
Esophagus : official journal of the Japan Esophageal Society
Apr 28, 2025
BACKGROUND: Detecting pathological complete response (pCR) preoperatively facilitated a non-surgical approach after neoadjuvant chemotherapy (NAC). We previously developed a deep neural network-based endoscopic evaluation to determine pCR preoperativ...
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