Exploring phenotypes to improve long-term mortality risk stratification in obstructive sleep apnea through a machine learning approach: an observational cohort study.

Journal: European journal of internal medicine
PMID: 39690003

Abstract

BACKGROUND: Obstructive sleep apnea (OSA) is a heterogeneous sleep disorder for which the identification of phenotypes might help for risk stratification for long-term mortality. Thus, the aim of the study was to identify distinct phenotypes of OSA and to study the association of phenotypes features with long-term mortality by using machine learning.

Authors

  • Pasquale Tondo
    Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy; Department of Specialistic Medicine, Pulmonary and Critical Care Unit, University-Hospital Polyclinic of Foggia, Foggia, Italy; Grenoble Alpes University, HP2 Laboratory, INSERM, CHU Grenoble Alpes, Grenoble, France. Electronic address: pasquale.tondo@unifg.it.
  • Giulia Scioscia
    Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy; Department of Specialistic Medicine, Pulmonary and Critical Care Unit, University-Hospital Polyclinic of Foggia, Foggia, Italy.
  • Sébastien Bailly
    HP2 laboratory, University of Grenoble Alpes, Grenoble, France.
  • Roberto Sabato
    Department of Specialistic Medicine, Pulmonary and Critical Care Unit, University-Hospital Polyclinic of Foggia, Foggia, Italy.
  • Terence Campanino
    Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy; Department of Specialistic Medicine, Pulmonary and Critical Care Unit, University-Hospital Polyclinic of Foggia, Foggia, Italy.
  • Piera Soccio
    Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
  • Maria Pia Foschino Barbaro
    Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
  • Crescenzio Gallo
    University of Foggia, Department of Clinical and Experimental Medicine; Foggia,Italy.
  • Jean-Louis Pépin
    University Grenoble Alpes Grenoble, France.
  • Donato Lacedonia
    Department of Medical and Occupational Sciences, Institute of Respiratory Disease, Università degli Studi di Foggia, Foggia, Italy.

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