AIMC Topic: Hypoxia

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Hypoxemia prediction in pediatric patients under general anesthesia using machine learning: A retrospective observational study and external validation.

PloS one
BACKGROUND: Pediatric patients under general anesthesia are particularly vulnerable to hypoxemia, which can lead to rapid oxygen desaturation. This vulnerability necessitates heightened vigilance from anesthesiologists, making pediatric anesthesia ma...

Exploring hypoxia- and cuproptosis-related biomarkers in periodontitis based on transcriptome and single-cell analysis.

Clinical oral investigations
BACKGROUND: Periodontitis (PD) is a chronic, multifactorial inflammatory disorder characterized by the progressive destruction of periodontal tissues. Increasing evidence indicates that the dysregulation of hypoxia-related genes (HRGs) plays a pivota...

Automated hypoxia and apnea identification for neonates via enhanced respiratory signal modeling with deep learning.

Scientific reports
Neonatal respiratory monitoring is crucial for assessing breathing patterns, but the lack of real-time clinical data limits the development of machine learning (ML) models. This study provides a synthetic signal generation framework to replicate infa...

Development and external validation of a machine learning model to predict high flow nasal cannula failure.

BMJ open respiratory research
INTRODUCTION: High-flow nasal cannula (HFNC) is an important treatment option for acute hypoxic respiratory failure and can improve outcomes. However, patients on a prolonged duration of HFNC have worse clinical outcomes and increased mortality. It i...

Development and validation of a bedside-available machine learning model to predict discrepancies between SaO₂ and SpO₂: Exploring factors related to the discrepancies.

PloS one
In critically ill patients, a discrepancy frequently exists between percutaneous oxygen saturation (SpO₂) and arterial blood oxygen saturation (SaO₂), which can lead to potential hypoxemia being overlooked. The aim of this study was to explore the fa...

AI-Driven Integration of Deep Learning With Lung Imaging, Functional Analysis, and Blood Gas Metrics for Perioperative Hypoxemia Prediction.

JMIR medical informatics
This viewpoint article explores the transformative role of artificial intelligence (AI) in predicting perioperative hypoxemia through the integration of deep learning with multimodal clinical data, including lung imaging, pulmonary function tests, an...

Machine learning unveils hypoxia-immune gene hub for clinical stratification of thyroid-associated ophthalmopathy.

Scientific reports
Thyroid-associated ophthalmopathy (TAO) is an autoimmune disorder affecting the orbit, potentially resulting in blindness. This study focused on the role of hypoxia in its pathogenesis through integrative bioinformatics and experimental validation. F...

Development and validation of a hypoxemia prediction model in middle-aged and elderly outpatients undergoing painless gastroscopy.

Scientific reports
Hypoxemia is a common complication associated with anesthesia in painless gastroscopy. With the aging of the social population, the number of cases of hypoxemia among middle-aged and elderly patients is increasing. However, tools for predicting hypox...

Promoting active health with AI technologies: Current status and prospects of high-altitude therapy, simulated hypoxia, and LLM-driven lifestyle rehabilitation approaches.

Bioscience trends
In the context of the rising global prevalence of obesity, traditional intervention measures have proven insufficient to meet the demands of personalized and sustainable health management, necessitating the exploration of innovative solutions through...

Intermittent hypoxemia during hemodialysis: AI-based identification of arterial oxygen saturation saw-tooth pattern.

BMC nephrology
BACKGROUND: Maintenance hemodialysis patients experience high morbidity and mortality, primarily from cardiovascular and infectious diseases. It was discovered recently that low arterial oxygen saturation (SaO) is associated with a pro-inflammatory p...