External validation of a deep learning model for automatic segmentation of skeletal muscle and adipose tissue on abdominal CT images.

Journal: The British journal of radiology
PMID: 39286936

Abstract

OBJECTIVES: Body composition assessment using CT images at the L3-level is increasingly applied in cancer research and has been shown to be strongly associated with long-term survival. Robust high-throughput automated segmentation is key to assess large patient cohorts and to support implementation of body composition analysis into routine clinical practice. We trained and externally validated a deep learning neural network (DLNN) to automatically segment L3-CT images.

Authors

  • David P J van Dijk
    Department of Surgery, Maastricht University Medical Center, Maastricht, 6200 MD, The Netherlands.
  • Leroy F Volmer
    Department of Radiotherapy (MAASTRO), Maastricht University, Maastricht, Maastricht, 6229 ET, The Netherlands.
  • Ralph Brecheisen
    Brain Innovation BV, Maastricht, Netherlands; Department of Cognitive Neuroscience, Faculty Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands.
  • Bibi Martens
  • Ross D Dolan
    Academic Unit of Surgery, School of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, Glasgow, G31 2ER, United Kingdom.
  • Adam S Bryce
    Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, Glasgow, G61 1BD, United Kingdom.
  • David K Chang
    Wolfson Wohl Cancer Research Centre, School of Cancer Sciences, University of Glasgow, Glasgow, Glasgow, G61 1BD, United Kingdom.
  • Donald C McMillan
    Academic Unit of Surgery, School of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, Glasgow, G31 2ER, United Kingdom.
  • Jan H M B Stoot
    Department of Surgery, Zuyderland Medical Centre, Geleen, 6162 BG, The Netherlands.
  • Malcolm A West
    Academic Unit of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, Southampton, SO16 6YD, United Kingdom.
  • Sander S Rensen
    Department of Surgery, Maastricht University Medical Center, Maastricht, 6200 MD, The Netherlands.
  • Andre Dekker
    Department of Radiation Oncology (MAASTRO Clinic), Dr. Tanslaan 12, Maastricht, The Netherlands.
  • Leonard Wee
    Maastricht University Medical Centre, Netherlands.
  • Steven W M Olde Damink
    Department of Surgery, Maastricht University Medical Center, Maastricht, 6200 MD, The Netherlands.

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