Developing a Predictive Model for Metastatic Potential in Pancreatic Neuroendocrine Tumor.

Journal: The Journal of clinical endocrinology and metabolism
PMID:

Abstract

CONTEXT: Pancreatic neuroendocrine tumors (PNETs) exhibit a wide range of behavior from localized disease to aggressive metastasis. A comprehensive transcriptomic profile capable of differentiating between these phenotypes remains elusive.

Authors

  • Jacques A Greenberg
    Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
  • Yajas Shah
    Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, Cornell University, New York, NY, 10065, USA.
  • Nikolay A Ivanov
    Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
  • Teagan Marshall
    Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
  • Scott Kulm
    Caryl and Israel Englander Institute of Precision Medicine, Weill Cornell Medicine, New York, NY.
  • Jelani Williams
    Department of Surgery, University of Chicago Medicine, Chicago, IL 60637, USA.
  • Catherine Tran
    Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
  • Theresa Scognamiglio
    Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Jonas J Heymann
    Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
  • Yeon J Lee-Saxton
    Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
  • Caitlin Egan
    Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
  • Sonali Majumdar
    Genomics Facility, The Wistar Institute, Philadelphia, PA 19104, USA.
  • Irene M Min
    Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
  • Rasa Zarnegar
    Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
  • James Howe
    Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
  • Xavier M Keutgen
    Department of Surgery, University of Chicago Medicine, Chicago, IL 60637, USA.
  • Thomas J Fahey
    Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
  • Olivier Elemento
    Institute for Precision Medicine.
  • Brendan M Finnerty
    Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.