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Neuroendocrine Tumors

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Radiomics machine learning algorithm facilitates detection of small pancreatic neuroendocrine tumors on CT.

Diagnostic and interventional imaging
PURPOSE: The purpose of this study was to develop a radiomics-based algorithm to identify small pancreatic neuroendocrine tumors (PanNETs) on CT and evaluate its robustness across manual and automated segmentations, exploring the feasibility of autom...

Automatic discrimination between neuroendocrine carcinomas and grade 3 neuroendocrine tumors by deep learning of H&E images.

Computers in biology and medicine
Neuroendocrine neoplasms (NENs) arise from diffuse neuroendocrine cells and are categorized as either well-differentiated and less proliferative Neuroendocrine Tumors (NETs), divided into low (G1), middle (G2), and high grades (G3), or poorly differe...

Random survival forest algorithm for risk stratification and survival prediction in gastric neuroendocrine neoplasms.

Scientific reports
This study aimed to construct and assess a machine-learning algorithm designed to forecast survival rates and risk stratification for patients with gastric neuroendocrine neoplasms (gNENs) after diagnosis. Data on patients with gNENs were extracted a...

Deep Learning and Automatic Differentiation of Pancreatic Lesions in Endoscopic Ultrasound: A Transatlantic Study.

Clinical and translational gastroenterology
INTRODUCTION: Endoscopic ultrasound (EUS) allows for characterization and biopsy of pancreatic lesions. Pancreatic cystic neoplasms (PCN) include mucinous (M-PCN) and nonmucinous lesions (NM-PCN). Pancreatic ductal adenocarcinoma (P-DAC) is the commo...

An endoscopic ultrasound-based interpretable deep learning model and nomogram for distinguishing pancreatic neuroendocrine tumors from pancreatic cancer.

Scientific reports
To retrospectively develop and validate an interpretable deep learning model and nomogram utilizing endoscopic ultrasound (EUS) images to predict pancreatic neuroendocrine tumors (PNETs). Following confirmation via pathological examination, a retrosp...

Deep Learning Enabled Scoring of Pancreatic Neuroendocrine Tumors Based on Cancer Infiltration Patterns.

Endocrine pathology
Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous group of neoplasms that include tumors with different histomorphologic characteristics that can be correlated to sub-categories with different prognoses. In addition to the WHO grading sc...

Endoscopic ultrasonography-based intratumoral and peritumoral machine learning ultrasomics model for predicting the pathological grading of pancreatic neuroendocrine tumors.

BMC medical imaging
OBJECTIVES: The objective is to develop and validate intratumoral and peritumoral ultrasomics models utilizing endoscopic ultrasonography (EUS) to predict pathological grading in pancreatic neuroendocrine tumors (PNETs).

The Role of AI in the Evaluation of Neuroendocrine Tumors: Current State of the Art.

Seminars in nuclear medicine
Advancements in Artificial Intelligence (AI) are driving a paradigm shift in the field of medical diagnostics, integrating new developments into various aspects of the clinical workflow. Neuroendocrine neoplasms are a diverse and heterogeneous group ...

Selection of neuroendocrine markers in diagnostic workup of neuroendocrine neoplasms: The real-world data and machine learning model algorithms.

Cancer cytopathology
BACKGROUND: Accurate diagnosis of neuroendocrine neoplasms (NENs) is challenging, especially in poorly differentiated neuroendocrine carcinomas (NECs). This study was aimed to search the best or best combination of neuroendocrine markers in the diagn...

A convolutional neural network-based system for identifying neuroendocrine neoplasms and multiple types of lesions in the pancreas using EUS (with videos).

Gastrointestinal endoscopy
BACKGROUND AND AIMS: EUS is sensitive in detecting pancreatic neuroendocrine neoplasm (pNEN). However, the endoscopic diagnosis of pNEN is operator-dependent and time-consuming because pNEN mimics normal pancreas and other pancreatic lesions. We inte...