AIMC Topic: Neuroendocrine Tumors

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Radiomics and artificial intelligence for predicting pituitary neuroendocrine tumor consistency: a systematic review and meta-analysis.

Neurosurgical review
Pituitary neuroendocrine tumors (PitNETs) represent approximately 16% of primary brain tumors. Tumor consistency, whether soft or hard, directly affects surgical strategy, extent of resection, and risk of complications. This study aimed to perform a ...

Experimental approach for optimizing dose regimen of 68Ga-DOTATATE PET/CT for neuroendocrine tumor (NET) imaging in current high sensitivity scanners: Phantom and Patient Study.

Nuklearmedizin. Nuclear medicine
This study aimed to determine the optimized scan time and injected activity regimen for clinical Ga DOTATATE PET/CT in neuroendocrine tumor imaging through an experimental approach without using machine learning techniques.A NEMA PET body phantom was...

Primary tumor resection: a new hope or an old illusion for patients with metastatic non-small cell lung neuroendocrine tumors?

World journal of surgical oncology
OBJECTIVES: This study aimed to investigate the impact of primary tumor resection (PTR) on survival outcomes for patients with metastatic non-small cell neuroendocrine tumors (mNSCLC-NETs), develop a predictive model to identify which patients may be...

Identification and tissue-level validation of ferroptosis-related genes in small intestinal neuroendocrine neoplasms based on machine learning.

BMC gastroenterology
BACKGROUND: Small intestinal neuroendocrine neoplasms (SI-NENs), a subgroup of neuroendocrine tumors originating from neuroendocrine cells in the small intestine, present significant therapeutic challenges, and their relationship with ferroptosis-a r...

Comparing non-machine learning vs. machine learning methods for Ki67 scoring in gastrointestinal neuroendocrine tumors.

Scientific reports
The Ki67 score is a crucial prognostic biomarker for neuroendocrine tumors, but its manual assessment is labor-intensive, requiring the counting of 500-2,000 cells in hotspots. Digital image analysis could streamline this process, yet few comprehensi...

The importance of education and training in neuroendocrine neoplasms: challenges and opportunities for multidisciplinary management.

Cancer treatment reviews
Neuroendocrine neoplasms (NENs) exemplify the challenges and opportunities inherent in managing rare cancers. Their rarity, biological heterogeneity, and diagnostic complexity necessitate a highly structured and multidisciplinary approach to patient ...

AI-enhanced patient-specific dosimetry in I-131 planar imaging with a single oblique view.

Scientific reports
This study aims to enhance the dosimetry accuracy in I planar imaging by utilizing a single oblique view and Monte Carlo (MC) validated dose point kernels (DPKs) alongside the integration of artificial intelligence (AI) for accurate dose prediction w...

Machine learning method based on radiomics help differentiate posterior pituitary tumors from pituitary neuroendocrine tumors and craniopharyngioma.

Scientific reports
Posterior pituitary tumors (PPTs) are rare neoplasms, but easily misdiagnosed as pituitary neuroendocrine tumor (PitNET) and craniopharyngioma. This study aimed to differentiate PPTs from PitNET and craniopharyngioma using a machine learning method b...

Enhancing patient-centered care with AI: a study of responses to neuroendocrine neoplasms queries.

Endocrine
INTRODUCTION: Large Language Models (LLMs) are increasingly used in oncology, but their application in neuroendocrine neoplasms (NENs) is still unexplored.

GALR1 and PENK serve as potential biomarkers in invasive non-functional pituitary neuroendocrine tumours.

Gene
BACKGROUND: Some nonfunctioning pituitary neuroendocrine tumor (NFPitNET) can show invasive growth, which increases the difficulty of surgery and indicates a poor prognosis. However, the molecular mechanism related to invasiveness remains to be furth...