Identification of ALDH2 as a novel target for the treatment of acute kidney injury in kidney transplantation based on WGCNA and machine learning algorithms and exploration of its potential mechanism of action using animal experiments.

Abstract

Authors

• Jinpu Peng
  Department of Pediatric Surgery, Guizhou Provincial People's Hospital, 83 Zhongshan East Road, Nanming, Guiyang, Guizhou 550002, China.
• Shili Wang
  Department of Pediatric Surgrey, Guizhou Provincial People's Hospital, Guiyang, China.
• Xingyu Pan
  Department of Pediatric Surgrey, Guizhou Provincial People's Hospital, Guiyang, China.
• Moudong Wu
  Department of Pediatric Surgery, Guizhou Provincial People's Hospital, 83 Zhongshan East Road, Nanming, Guiyang, Guizhou 550002, China.
• Xiong Zhan
  School of Aerospace Engineering and Applied Mechanics, Tongji University, Shanghai 200092, People's Republic of China.
• Dan Wang
  Guangdong Pharmaceutical University Guangzhou Guangdong China.
• Guohua Zhu
  Department of Pediatric Surgrey, Guizhou Provincial People's Hospital, Guiyang, China.
• Wei Wang
  State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China.
• Hongyu Tang
  School of Electrical and Information, Zhenjiang College, Zhenjiang, Jiangsu, 212028, China. t_redrain@126.com.
• Nini An
  Department of Pediatric Surgery, Guizhou Provincial People's Hospital, 83 Zhongshan East Road, Nanming, Guiyang, Guizhou 550002, China.
• Jun Pei
  Department of Chemistry and the Department of Biochemistry and Molecular Biology, Michigan State University, 578 South Shaw Lane, East Lansing, Michigan 48824, United States.

Keywords

External Resources