Prediction of clinical deterioration within one year in chronic obstructive pulmonary disease using the systemic coagulation-inflammation index: a retrospective study employing multiple machine learning method.

Journal: PeerJ
PMID: 40028201

Abstract

BACKGROUND: Inflammatory response and the coagulation system are pivotal in the pathogenesis of clinical deterioration in chronic obstructive pulmonary disease (COPD), prompting us to hypothesize that the systemic coagulation-inflammation (SCI) index is associated with clinical deterioration in COPD.

Authors

  • Ling Hou
    Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao SAR, China.
  • Ming Min
    Department of Pulmonary and Critical Care Medicine, Central Hospital of Tujia and Miao Autonomous Prefecture, Enshi, China.
  • Rui Hou
    Guangzhou KangRui Biological Pharmaceutical Technology Company, 510005 Guangzhou, China.
  • Wei Tan
    Weifang People's Hospital, Guang Wen Road, Weifang 261000, China.
  • Minghua Zhang
    Zhejiang Province Key Laboratory of Watershed Science and Health, Southern Zhejiang Water Research Institute (iWATER), Wenzhou Medical University, Wenzhou, 325035, China. mhzhang@ucdavis.edu.
  • Qianfei Liu
    Department of Pulmonary and Critical Care Medicine, Central Hospital of Tujia and Miao Autonomous Prefecture, Enshi, China.

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