AIMC Topic: Pulmonary Disease, Chronic Obstructive
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Lysophospholipid metabolism, clinical characteristics, and artificial intelligence-based quantitative assessments of chest CT in patients with stable COPD and healthy smokers.
Scientific reports
Jul 21, 2025
The specific role of lysophospholipids (LysoPLs) in the pathogenesis of chronic obstructive pulmonary disease (COPD) is not yet fully understood. We determined serum LysoPLs in 20 patients with stable COPD and 20 healthy smokers using liquid chromato...
Assessing inflammatory protein biomarkers in COPD subjects with and without alpha-1 antitrypsin deficiency.
Respiratory research
Jul 15, 2025
RATIONALE: Individuals homozygous for the Alpha-1 Antitrypsin (AAT) Z allele (Pi*ZZ) exhibit heterogeneity in COPD risk. COPD occurrence in non-smokers with AAT deficiency (AATD) suggests that inflammatory processes may contribute to COPD risk indepe...
Assessing chronic obstructive pulmonary disease risk based on exhalation and cough sounds.
Biomedical engineering online
Jul 5, 2025
BACKGROUND AND OBJECTIVE: Chronic obstructive pulmonary disease (COPD), a progressively worsening respiratory condition, severely impacts patient quality of life. Early risk assessment can improve treatment outcomes and lessen healthcare burdens. How...
Construction and validation of a risk prediction model for chronic obstructive pulmonary disease (COPD): a cross-sectional study based on the NHANES database from 2009 to 2018.
BMC pulmonary medicine
Jul 3, 2025
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a major global public health concern, and early screening and identification of high-risk populations are critical for reducing the disease burden. Although several studies have explored the...
Development and validation of a risk prediction model for depression in patients with chronic obstructive pulmonary disease.
BMC psychiatry
Jul 3, 2025
BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a prevalent respiratory condition often accompanied by depression, which exacerbates disease burden and impairs quality of life. Early identification of depression risk in COPD patients rema...
Effectiveness of Digital Health Interventions for Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis.
Journal of medical Internet research
May 26, 2025
BACKGROUND: Chronic obstructive pulmonary disease (COPD), marked by dyspnea, cough, and sputum production, significantly impairs patients' quality of life and functionality. Effective management strategies, particularly those empowering patients to m...
Step up to triple therapy versus switch to dual bronchodilator therapy in patients with COPD on an inhaled corticosteroid/long-acting β-agonist: post-hoc analyses of KRONOS.
Respiratory research
May 8, 2025
BACKGROUND: In people with chronic obstructive pulmonary disease (COPD) on inhaled corticosteroid/long-acting β-agonist (ICS/LABA) therapy, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends stepping up to ICS/long-acting mu...
Drug Combinations
Double-Blind Method
Adrenergic beta-2 Receptor Agonists
Muscarinic Antagonists
Humans
Drug Therapy, Combination
Adrenal Cortex Hormones
Drug Substitution
Administration, Inhalation
Bronchodilator Agents
Pulmonary Disease, Chronic Obstructive
Male
Middle Aged
Treatment Outcome
Female
Aged
The Role of Computed Tomography and Artificial Intelligence in Evaluating the Comorbidities of Chronic Obstructive Pulmonary Disease: A One-Stop CT Scanning for Lung Cancer Screening.
International journal of chronic obstructive pulmonary disease
May 6, 2025
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Comorbidities in patients with COPD significantly increase morbidity, mortality, and healthcare costs, posing a significant burden on the management o...
Identification and verification of mitochondria-related genes biomarkers associated with immune infiltration for COPD using WGCNA and machine learning algorithms.
Scientific reports
Apr 24, 2025
Mitochondrial dysfunction plays a pivotal role in the pathogenesis of chronic obstructive pulmonary disease (COPD). This study combines bioinformatics analysis with machine learning to elucidate potential key mitochondrial-related genes associated wi...
The predictive role of identifying frailty in assessing the need for palliative care in the elderly: the application of machine learning algorithm.
Journal of health, population, and nutrition
Apr 23, 2025
BACKGROUND: Palliative care is a key component of integrated care to improve care quality and reduce hospitalization costs for patients with chronic obstructive pulmonary disease (COPD). This study aims to use machine learning algorithms to create an...
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