AIMC Topic: Pulmonary Disease, Chronic Obstructive
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Development and validation of a risk prediction model for depression in patients with chronic obstructive pulmonary disease.
BMC psychiatry
Jul 3, 2025
BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a prevalent respiratory condition often accompanied by depression, which exacerbates disease burden and impairs quality of life. Early identification of depression risk in COPD patients rema...
Effectiveness of Digital Health Interventions for Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-Analysis.
Journal of medical Internet research
May 26, 2025
BACKGROUND: Chronic obstructive pulmonary disease (COPD), marked by dyspnea, cough, and sputum production, significantly impairs patients' quality of life and functionality. Effective management strategies, particularly those empowering patients to m...
Step up to triple therapy versus switch to dual bronchodilator therapy in patients with COPD on an inhaled corticosteroid/long-acting β-agonist: post-hoc analyses of KRONOS.
Respiratory research
May 8, 2025
BACKGROUND: In people with chronic obstructive pulmonary disease (COPD) on inhaled corticosteroid/long-acting β-agonist (ICS/LABA) therapy, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends stepping up to ICS/long-acting mu...
Adrenergic beta-2 Receptor Agonists
Drug Combinations
Muscarinic Antagonists
Double-Blind Method
Humans
Adrenal Cortex Hormones
Pulmonary Disease, Chronic Obstructive
Drug Therapy, Combination
Female
Administration, Inhalation
Male
Drug Substitution
Bronchodilator Agents
Aged
Middle Aged
Treatment Outcome
The Role of Computed Tomography and Artificial Intelligence in Evaluating the Comorbidities of Chronic Obstructive Pulmonary Disease: A One-Stop CT Scanning for Lung Cancer Screening.
International journal of chronic obstructive pulmonary disease
May 6, 2025
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Comorbidities in patients with COPD significantly increase morbidity, mortality, and healthcare costs, posing a significant burden on the management o...
Identification and verification of mitochondria-related genes biomarkers associated with immune infiltration for COPD using WGCNA and machine learning algorithms.
Scientific reports
Apr 24, 2025
Mitochondrial dysfunction plays a pivotal role in the pathogenesis of chronic obstructive pulmonary disease (COPD). This study combines bioinformatics analysis with machine learning to elucidate potential key mitochondrial-related genes associated wi...
The predictive role of identifying frailty in assessing the need for palliative care in the elderly: the application of machine learning algorithm.
Journal of health, population, and nutrition
Apr 23, 2025
BACKGROUND: Palliative care is a key component of integrated care to improve care quality and reduce hospitalization costs for patients with chronic obstructive pulmonary disease (COPD). This study aims to use machine learning algorithms to create an...
An integrated machine learning model of transcriptomic genes in multi-center chronic obstructive pulmonary disease reveals the causal role of TIMP4 in airway epithelial cell.
Respiratory research
Apr 23, 2025
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome, resulting in inconsistent findings across studies. Identifying a core set of genes consistently involved in COPD pathogenesis, independent of patient variability, i...
Bioinformatics Approach to Identifying Molecular Targets of Isoliquiritigenin Affecting Chronic Obstructive Pulmonary Disease: A Machine Learning Pharmacology Study.
International journal of molecular sciences
Apr 21, 2025
To identify the molecular targets and possible mechanisms of isoliquiritigenin (ISO) in affecting chronic obstructive pulmonary disease (COPD) by regulating the glycolysis and phagocytosis of alveolar macrophages (AM). Datasets GSE130928 and GSE13896...
Risk prediction for acute kidney disease and adverse outcomes in patients with chronic obstructive pulmonary disease: an interpretable machine learning approach.
Renal failure
Apr 7, 2025
BACKGROUND: Little is known about acute kidney injury (AKI) and acute kidney disease (AKD) in patients with chronic obstructive pulmonary disease (COPD) and COPD mortality based on the acute/subacute renal injury. This study develops machine learning...
Land surface temperature predicts mortality due to chronic obstructive pulmonary disease: a study based on climate variables and impact machine learning.
Geospatial health
Mar 26, 2025
INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD) mortality rates and global warming have been in the focus of scientists and policymakers in the past decade. The long-term shifts in temperature and weather patterns, commonly referred to as ...
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