Improving Outcomes in Hepatocellular Carcinoma through Integration of Machine Learning: Development of a Tumor-Associated Macrophage Signature.

Journal: Digestive diseases (Basel, Switzerland)
PMID: 39894017

Abstract

INTRODUCTION: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors globally. Macrophages, as essential components of the immune system, play crucial roles in immune regulation, inflammation modulation, and antitumor activity. However, it remains unclear whether tumor-associated macrophages can serve as prognostic markers for HCC.

Authors

  • Zicheng Zhou
    Department of Gastroenterology, Affiliated Hospital of Nantong University, Nantong, China, zichengzh@foxmail.com.
  • Sijia Ge
    Department of Gastroenterology, Affiliated Hospital of Nantong University, Nantong, China.
  • Chiyu Gu
    Department of Gastroenterology, Affiliated Hospital of Nantong University, Nantong, China.
  • Jing Chen
    Department of Vascular Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
  • Cuihua Lu
    Department of Gastroenterology, Affiliated Hospital of Nantong University, Nantong, China.
  • Yanhua Liu
    Department of Gastroenterology, Affiliated Hospital of Nantong University, Nantong, China.
  • Sutian Jiang
    Department of Pathology, Lishui People's Hospital, Lishui, China.

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