Machine Learning Analysis of Nutrient Associations with Peripheral Arterial Disease: Insights from NHANES 1999-2004.

Journal: Annals of vascular surgery
PMID:

Abstract

BACKGROUND: Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis, affecting over 200 million people worldwide. The incidence of PAD is increasing due to the aging population. Common risk factors include smoking, diabetes, and hyperlipidemia, but its exact pathogenesis remains unclear. Nutritional intake is associated with the onset and progression of PAD, although relevant studies remain limited. Some studies suggest that certain nutritional elements may influence the development of PAD. This study aims to explore the relationship between nutrition and PAD using machine learning techniques. Unlike traditional statistical methods, machine learning can effectively capture complex, nonlinear relationships, providing a more comprehensive analysis of PAD risk factor.

Authors

  • Yi-Xuan Wang
    College of Integrated Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan Province, China. Electronic address: wangyyyxuan@163.com.
  • Jin-Quan Kang
    Beijing Information Science & Technology University, Beijing, China.
  • Zuo-Guan Chen
    Department of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Shang Gao
    Department of Orthopedics, Orthopedic Center of Chinese PLA, Southwest Hospital, Third Military Medical University, Chongqing, 400038, P.R.China.
  • Wen-Xin Zhao
    Department of Thyroid Surgery, Fujian Medical University Union Hospital, Fujian, Fuzhou, China.
  • Ning Zhao
  • Yong Lan
    Department of Radiology, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Guangdong Medical University, Affiliated Jiangmen Hospital of SUN YAT-SEN University, 23 Beijie Haibang Street, Jiangmen, 529030, China.
  • Yong-Jun Li
    School of Computer Science, Northwestern Polytechnical University, Xi'an, Shaanxi 710072, China.