Effects of Rivaroxaban Therapy on ROTEM Coagulation Parameters in Patients with Venous Thromboembolism.

Journal: Advances in clinical and experimental medicine : official organ Wroclaw Medical University
PMID:

Abstract

BACKGROUND: Rivaroxaban (Xarelto) does not require routine coagulation monitoring; however, in certain clinical situations (overdose, drug accumulation, urgent surgery) measurement of its plasma concentration is highly recommended. Currently, there is no single hemostasis test that shows a direct correlation between rivaroxaban plasma levels and anticoagulant efficacy.

Authors

  • Krzysztof Chojnowski
    Department of Hematology, Medical University of Lodz, Poland.
  • Tomasz Górski
    Department of Hematology, Medical University of Lodz, Poland.
  • Marta Robak
    Department of Hematology, Medical University of Lodz, Poland.
  • Jacek Treliński
    Department of Hematology, Medical University of Lodz, Poland.